This article was just created or updated by Casey R Hayes.  The article details are listed below:

1. Check the status of Print Spooler service (services.msc)
2. If spooler is stopped, start spooler service
3. If spooler stops shortly after, delete all files/folders in the following directory -- C:\WINDOWS\system32\spool\PRINTERS\ -- If C:\WINDOWS\system32\spool\PRINTERS is already empty, continue to step 6.
4. Start the spooler & test.  If problem is NOT resolved, continue to step 5 (most likely a corrupt printer driver).
5. Backup the following registry key -- HKLM\System\CurrentControlSet\Control\Print\Environments\Windows x64\Drivers
6. Delete printers from Version-3 & Version-4 that were not software/builtin printers (may be located in Windows x64 -- depends on installed OS)
7. Reboot PC
8. Reinstall & configure printers

NOTE: If printers are pushed out by GPO, you do not have to complete step 8.